Dubin Johnson syndrome Dubin-Johnson syndrome is a rare autosomal recessive inherited disorder of bilirubin transport that is characterized by buildup of bilirubin in the bloodstream (conjugated hyperbilirubinemia),
What is hyperbilirubinemia Hyperbilirubinemia is a medical condition characterized by elevated levels of bilirubin (an orange-yellow pigment formed in the liver by the breakdown of hemoglobin)
What is carotenemia Carotenemia is the term used for increased beta-carotene levels in the blood and yellow pigmentation of the skin. Strictly speaking, excessive carotene
Crigler Najjar syndrome Crigler-Najjar syndrome is a very rare inherited disorder characterized by a persistent high levels of a toxic substance called unconjugated bilirubin in
Pyruvate kinase deficiency Pyruvate kinase deficiency is an inherited disorder that affects red blood cells, which carry oxygen to the body's tissues. People with pyruvate
ABO incompatibility ABO incompatibility is the most common cause of hemolytic disease of the newborn (HDN) which occurs in 15 to 25% of pregnancies ((Murray
Vitamin K3 Vitamin K3 also called menadione or 2-methyl-1,4-naphthoquinone is a man-made (synthetic) water soluble analogue of vitamin K (a family of compounds with a common chemical structure
Unconjugated bilirubin Unconjugated bilirubin also known as indirect bilirubin, is a fat-soluble form of bilirubin that is formed during the initial chemical breakdown of hemoglobin
Ubiquinone Ubiquinone also called coenzyme Q10 (CoQ10), ubidecarenone or vitamin Q10 is a benzoquinone compound (a fat-soluble vitamin K-like molecule) that is naturally present in the
Idebenone Idebenone is a synthetic (man-made) short-chain benzoquinone (6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone) and a synthetic analog of coenzyme Q10 (CoQ10) that is used as a substrate for the enzyme